There can be a theoretical explanation for any combination of notes. I use a lot of dissonance in my music. Clashes with neighboring half-tones can even be used effectively, like C/Db. The stacking order of notes determine the chord name, e.g., an Eb6 chord (Eb,G,Bb,C) built on the root note “C” (C,Eb,G,Bb) becomes a Cm7 chord. So the bass note can alter the name of a chord. Bottom-line... if it sounds good to you, that's all that matters. No right or wrong.

John smile